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The Catellani reaction was devised by Marta Catellani. It is Norbornene-mediated Ortho C-H functionalization consisting series of reaction. Norbornene acts as a catalyst in this reaction. == Reaction mechanism == The Catellani reaction is catalyzed by norbornene and palladium. The key step is the formation of a palladacycle by electrophilic metalation at the ortho position followed by deprotonation and rearomatization. The unique structure of the norbornene allows this step to occur because there is no possibility of beta hydride elimination with the bridgehead hydrogen. Termination can occur by any of a number of traditional palladium-catalyzed coupling reactions. Rhodium can also be used as a catalyst along with norbornene instead of Palladium. Steps of the Catellani reaction: # Oxidative addition # Carbopalladation of norbornene # Palladacycle formation # Oxidative addition to palladacycle # Reductive elimination from palladacycle # Norbornene extrusion # Termination via Heck reaction, Suzuki reaction, etc. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Catellani Reaction」の詳細全文を読む スポンサード リンク
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